Approximately one in three men suffer from ED, and when combined with mild symptoms, an estimated 18 million men experience the symptoms.
The etiology may involve psychological factors; however, in men over 40, organic factors are predominantly responsible. These typically include vascular aging and damage to blood vessels stemming from conditions such as diabetes, hypertension, and other comorbidities.
Erectile Dysfunction Medication
Medications such as Cialis, Levitra, and Viagra are available nationwide, and obtaining prescriptions through online diagnosis is now straightforward. However, many individuals are reluctant to continue using these medications.
Concerns about Side Effects
Medications function by acutely increasing blood flow, which can lead to various side effects depending on their use and frequency. Common side effects include flushing and headaches. Less frequently, patients may experience irregular heartbeat, dizziness, hypertension, and dyspnea. In severe cases, this can result in a myocardial infarction.
If erectile dysfunction is caused by hypertension, pharmacological intervention may, in fact, elevate blood pressure. Consequently, many patients are reluctant to use medication, even when concerned about their condition.
Matters Pertaining to Men's Dignity and Life
Irrespective of age, Erectile Dysfunction is a significant issue affecting male dignity. However, more profoundly, it often conceals serious underlying life issues.
The most common cause of organic ED is vascular aging. Erections occur when blood flows into the corpora cavernosa. That is, when blood vessels are damaged or narrowed due to atherosclerosis, blood flow to the penis is impaired, making erections difficult or not sufficiently firm.
Blood vessels are distributed throughout the entire body, and penile blood vessels do not spontaneously sustain damage. All blood vessels in the body undergo aging.
To illustrate: consider vascular damage to penile arteries in erectile dysfunction (ED), coronary arteries of the heart in angina, and cerebral arteries in stroke. The diameters of these vessels differ significantly. Penile arteries typically measure 1-2 mm in diameter, coronary arteries 3-4 mm, and carotid arteries 5-6 mm. Given that atherosclerosis tends to develop in smaller caliber vessels, it is highly probable that coronary arteries will become occluded after penile arteries.
Age should not be a deterrent. It is crucial to detect signs of serious diseases early through ED, review one's lifestyle, and proactively address the aging process.
From the age of 40 onwards, temporary recovery is insufficient; root cause treatment with regenerative therapy is essential.
Domestically Available Regenerative Therapy
In recent years, regenerative therapies utilizing stem cell conditioned medium or exosomes have emerged as a topic in aesthetics and anti-aging. However, why is their efficacy not widely discussed?
This is attributed to the fact that the expected effects are not universally observed, leading to doubts about its true efficacy on an individual level. Consequently, some individuals are hesitant to embrace this treatment method. Additionally, a contributing factor to the limited public awareness of this treatment modality may be that many people struggle to conceptualize what regenerative therapy entails and lack comprehensive understanding of the production and mechanisms of action of the biological components utilized.
Stem Cell Culture Fluid and Exosomes
It is often overlooked how many effective components are contained within stem cell culture medium or exosomes.
Stem cell-conditioned medium
Kekurangan dan Risiko:Not everything secreted during stem cell cultivation is good. There are cases where fluid harvested from cultured cells for the treatment of others is used directly. Firstly, stem cell culture fluid is a fluid that contains components for stem cell growth, so the effective components are spread out. Furthermore, while safety standards for stem cell cultivation are clear, the safety of serum production is questionable.
Stem cell culture media contain numerous components designed to enhance stem cell proliferation. In the event of bacterial or viral infection, stem cell proliferation is significantly compromised. Cultures lacking established safety standards carry a high risk of infection. Additionally, some culture media incorporate anti-infective agents to prevent infection. However, these often contain numerous superfluous additives, outnumbering components with actual therapeutic effects.
Exosome
Kekurangan dan Risiko:Exosomes actually cannot work alone. Therefore, it is necessary to contain secretory substances in balance, in addition to exosomes. Even if it contains many exosomes, if they are only exosomes, it means nothing. Exosomes are in our bodies. To exert an effect, it is necessary to choose which exosome serves what purpose, and from which cell it is secreted. There are also cases where they are secreted from cancer cells or other diseased cells, and there is a possibility of increasing the risk of disease.
While regenerative therapy holds promise for root healing, patients and the clinicians providing it must avoid high-risk interventions and possess the knowledge to distinguish those with high therapeutic efficacy.
Highly Safe and Scientifically Proven 23rd Century Regenerative Therapy
Stem cell-secreted substances are known to contain bioactive cellular components. Their therapeutic efficacy is a subject of extensive global research, with new findings reported daily. These findings are typically documented in scientific papers, which constitute scientific evidence.
Notably, Malaysia pioneered regenerative therapy prior to Japan. Consequently, stringent safety standards have been established for the cultivation of stem cells and their secretomes. Furthermore, the exchange of technology and sharing of evidence between the relevant countries have been highly active, and a wealth of clinical data is available.
Stem cells genuinely secrete cell-activating substances, and among these, safe and effective ones are selected. Currently, in advanced regenerative therapy countries, including Malaysia, a production method has been developed to effectively extract beneficial substances, moving beyond the use of crude "cultured stem cell secretions" such as stem cell culture serum. This extract is termed "secretome," which includes exosomes, a relatively new term. Regenerative therapy utilizing this secretome is now recognized to have numerous therapeutic effects.
Malaysia has limited the number of manufacturing facilities certified to the highest Malaysian cGMP standards for cGTP (Cell and Gene Therapy Products) to just three. Of these, the sole facility capable of manufacturing products suitable for patient treatment is 23Century International Life Science Center (hereinafter referred to as 23C).
23C manufactures a safe and effective secretome at their own facility. Patients from around the world seek treatment for erectile dysfunction (ED) utilizing this secretome, and we have received considerable positive feedback regarding its efficacy. A subset of patients undergoing ED treatment also receives regenerative therapy for severe vascular-related conditions.
Building deep trust through results. That is the most important mission of 23C.